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関連する概念動画

Defenses Against Pathogens and Herbivores02:26

Defenses Against Pathogens and Herbivores

Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.
Overview of Cell Death01:30

Overview of Cell Death

Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the 20th century...
The Extrinsic Apoptotic Pathway01:17

The Extrinsic Apoptotic Pathway

The extrinsic apoptotic pathway is initiated when extracellular death-inducing signals, such as specific cytokines, activate the death receptors expressed on the cell surface. The immune cells involved in this pathway are natural killer cells (NK cells) and cytotoxic T-lymphocytes. NK cells are critical in innate immune response, while cytotoxic T-lymphocytes are associated with adaptive immune response. These cells recognize specific receptors expressed on the altered cells and activate...
Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
Cellular Injury IlI: Cellular Death01:11

Cellular Injury IlI: Cellular Death

Cell death is the irreversible loss of cellular structure and function, representing the final stage of severe injury. It plays a key role in both normal physiology and disease.Types of Cell DeathThe two main types are necrosis and apoptosis, though others like necroptosis and pyroptosis also exist.Necrosis:Necrosis is an unregulated form of cell death caused by severe injury such as trauma, toxins, or ischemia. It is characterized by cell swelling, membrane loss, rupture, and leakage of...
Cellular Injury V: Apoptosis and Autophagy01:22

Cellular Injury V: Apoptosis and Autophagy

Cells respond to damage and stress through highly coordinated processes that decide whether they survive or undergo controlled self-destruction. Two major pathways involved in this regulation are apoptosis, a type of programmed cell death, and autophagy, a survival mechanism that helps cells adapt to adverse conditions.ApoptosisApoptosis removes aged or injured cells to maintain tissue balance. During this process, the cell shrinks, chromatin condenses and fragments, and membrane-bound...

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関連する実験動画

Updated: Jul 22, 2026

Assay for Pathogen-Associated Molecular Pattern (PAMP)-Triggered Immunity (PTI) in Plants
08:45

Assay for Pathogen-Associated Molecular Pattern (PAMP)-Triggered Immunity (PTI) in Plants

Published on: September 9, 2009

植物のプログラム細胞死:病原体が誘発する反応が,複数の防御機能と協調して活性化される.

J T Greenberg1, A Guo, D F Klessig

  • 1Department of Genetics, Harvard Medical School, Boston, Massachusetts.

Cell
|May 20, 1994
PubMed
まとめ

加速細胞死2 (ACD2) 遺伝子が欠けている変異性アラビドプシス・タリアナ植物では,自発的に過敏反応 (HR) が発現します. これは,ACD2が通常,植物のプログラム細胞死を抑制することを示唆しています.

科学分野:

  • 植物病理学 植物病理学
  • 分子遺伝学 分子遺伝学
  • 細胞生物学 細胞生物学

背景:

  • 過敏反応 (HR) は,急速な細胞死を含む植物防御機構です.
  • HRは通常,病原体感染によって引き起こされ,プログラムされた細胞死経路を含むと考えられています.

研究 の 目的:

  • 植物におけるプログラム細胞死を調節する加速細胞死2 (ACD2) 遺伝子の役割を調査する.
  • acd2変異植物で観察された自発的なHR型フェノタイプを特徴づける.

主な方法:

  • アラビドプシス・タリアナ変異体の遺伝子解析.
  • acd2植物における自発的な病変のフェノタイプ的特徴.
  • 防衛関連の遺伝子発現とHRに関連した分子マーカーの分析.

主要な成果:

  • ACD2遺伝子に病変がある変異種アラビドプシス・タリアナは,病原体に曝露することなく,自発的にHRのような症状を発現した.
  • これらの自発的な病変は,細胞壁の変異,病原体に対する耐性,サリチル酸および抗微生物化合物の蓄積を含むHRの典型的な特徴を示した.
  • 防衛関連の遺伝子トランスクリプトも,影響を受けた組織で上昇した.

さらに関連する動画

A β-glucuronidase (GUS) Based Cell Death Assay
07:35

A β-glucuronidase (GUS) Based Cell Death Assay

Published on: May 6, 2011

Bacterial Leaf Infiltration Assay for Fine Characterization of Plant Defense Responses using the Arabidopsis thaliana-Pseudomonas syringae Pathosystem
11:50

Bacterial Leaf Infiltration Assay for Fine Characterization of Plant Defense Responses using the Arabidopsis thaliana-Pseudomonas syringae Pathosystem

Published on: October 1, 2015

関連する実験動画

Last Updated: Jul 22, 2026

Assay for Pathogen-Associated Molecular Pattern (PAMP)-Triggered Immunity (PTI) in Plants
08:45

Assay for Pathogen-Associated Molecular Pattern (PAMP)-Triggered Immunity (PTI) in Plants

Published on: September 9, 2009

A β-glucuronidase (GUS) Based Cell Death Assay
07:35

A β-glucuronidase (GUS) Based Cell Death Assay

Published on: May 6, 2011

Bacterial Leaf Infiltration Assay for Fine Characterization of Plant Defense Responses using the Arabidopsis thaliana-Pseudomonas syringae Pathosystem
11:50

Bacterial Leaf Infiltration Assay for Fine Characterization of Plant Defense Responses using the Arabidopsis thaliana-Pseudomonas syringae Pathosystem

Published on: October 1, 2015

結論:

  • ACD2遺伝子は,植物のプログラム細胞死経路を否定的に調節する上で重要な役割を果たしています.
  • ACD2機能の喪失は,過敏反応の自発的な活性化につながり,HRを抑制する機能を示す.
  • ACD2は,植物細胞死と防御の遺伝子制御の重要な構成要素です.