関連する実験動画

Updated: Aug 10, 2026

Simultaneous Quantification of T-Cell Receptor Excision Circles (TRECs) and K-Deleting Recombination Excision Circles (KRECs) by Real-time PCR
14:14

Simultaneous Quantification of T-Cell Receptor Excision Circles (TRECs) and K-Deleting Recombination Excision Circles (KRECs) by Real-time PCR

Published on: December 6, 2014

ZAP-70欠乏症は,重症複合免疫欠乏症の自己相性後退型である

A C Chan1, T A Kadlecek, M E Elder

  • 1Howard Hughes Medical Institute, Department of Medicine, University of California, San Francisco 94143.

Science (New York, N.Y.)
|June 10, 1994
PubMed
まとめ

3人の兄弟の重症複合免疫不全症 (SCID) は,タンパク質チロシンキナーゼ (PTK) であるZAP-70の欠乏から生じた. この欠乏がT細胞受容体 (TCR) 信号伝達に欠陥をもたらし,ZAP-70の重要な役割を強調した.

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