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GTPガンマSと複合したトランスデューシン-アルファの2.2A結晶構造

J P Noel1, H E Hamm, P B Sigler

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510.

Nature
|December 16, 1993
PubMed
まとめ

活性化されたトランスデューシンの結晶構造は,GTP結合がどのようにその機能を調節するかを明らかにします. これは,Gタンパク質シグナル伝達におけるヌクレオチド交換,エフェクタ結合,GTPアゼ活性に関する洞察を提供します.

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