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Updated: Aug 17, 2026

RNA Catalyst as a Reporter for Screening Drugs against RNA Editing in Trypanosomes
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U6-U4RNA複合体から派生したRNAドメインの触媒活性

J H Yang1, R Cedergren, B Nadal-Ginard

  • 1Howard Hughes Medical Institute, Department of Cellular and Molecular Physiology, Harvard Medical School, Boston, MA.

Science (New York, N.Y.)
|January 7, 1994
PubMed
まとめ

プレ-mRNAスプライシングに不可欠なU6-U4RNA複合体は,ハンマーヘッドリボ酵素に似た保存ドメインを有しています. 特定の変異により,この複合体はRNA分裂活性を示すことができ,スプライシングにおける触媒的役割を示唆する.

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