モンゴル・ジャービルの獲得特性のホルモン媒介の遺伝

M M Clark¹, P Karpiuk, B G Galef

¹Department of Psychology, McMaster University, Hamilton, Ontario, Canada.

Nature

|August 19, 1993

まとめ

子宮内で雄の兄弟に接触した雌のネズミの胎児は,アンドロゲン化され,成人の行動が変化します. これらの母親は,より多くの雄の子孫を生み出し,アンドロゲン化された特性を娘に受け継ぐ傾向があります.

科学分野:

発達生物学発達生物学とは
動物の行動動物の行動
エンドクリノロジーエンドクリノロジー

背景:

子宮内位置は,胎児の発達とネズミの成人フェノタイプに影響する.
子宮内でのアンドロゲンへの曝露は,形態学や行動に重大な変化をもたらす可能性があります.
以前の研究では,子宮内置の性特異的な効果が示されています.

研究の目的:

モンゴル・ジャービルの子宮内位置が子孫の性別比率に与える影響を調査する.
子宮内で雄の胎児に暴露された成虫の雌ゲルビルが,雌の胎児に暴露された雌ゲルビルと比較して異なる子育てをするかどうかを判断する.
アンドロゲニゼーション現象の世代間継承を調査する.

主な方法:

成人した雌のモンゴル・ジャービルの子宮内置位置 (雄と雌の間で妊娠) による子宮内置位置を基に子宮内置の性別比率を比較.
モンゴル・ジャービルの生殖に関する観察的研究.
子宮内曝露に関連した母子および子孫のフェノタイプの分析.

主要な成果:

男性の胎児の間に妊娠した雌のゲルビルは,かなり高い割合の息子を産んだ.
男性と妊娠した母親の娘は,子宮内でアンドロゲン化される可能性が高くなりました.
アンドロゲン化されたフェノタイプが世代を超えて遺伝する傾向が観察されました.

結論:

子宮内位置は,ゲルビルの子孫の性別比に影響を与えます.
子宮内のアンドロゲニゼーションは,母親の生殖戦略に影響を与える可能性があります.
この研究は,哺乳類における発達現象型の遺伝のための潜在的なメカニズムを示唆しています.

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