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Updated: Nov 2, 2025

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
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bcl-2に関連する遺伝子であるbcl-xは,アポプトティック細胞死亡の支配的なレギュレータとして機能する

L H Boise1, M González-García, C E Postema

  • 1Howard Hughes Medical Institute, Department of Medicine, University of Chicago, Illinois 60637.

Cell
|August 27, 1993
PubMed
まとめ

私たちは,プログラム細胞死 (アポトーシス) を調節する遺伝子であるbcl-xを発見しました. その2つの形態であるbcl-xLとbcl-xSは,細胞生存と死において対極的な役割を果たし,細胞周回と長寿に影響を与えます.

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