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Updated: May 7, 2026

Examining BCL-2 Family Function with Large Unilamellar Vesicles
08:35

Examining BCL-2 Family Function with Large Unilamellar Vesicles

Published on: October 5, 2012

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Bcl-2は,保存されたホモログであるバックスとインビヴォで異体分解し,プログラムされた細胞死を加速する

Z N Oltvai1, C L Milliman, S J Korsmeyer

  • 1Howard Hughes Medical Institute Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110.

Cell
|August 27, 1993
PubMed
まとめ

Bcl-2タンパク質はアポトーシスを抑制する. 研究者らは,Bcl-2と相互作用するタンパク質パートナーであるバックスを発見し,細胞死経路に影響を与えました. Bcl-2とBaxの比率は,細胞生存またはアポトーシスを決定する.

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