TFII-IMyc

A L Roy1, C Carruthers, T Gutjahr

  • 1Laboratory of Biochemistry and Molecular Biology, Rockefeller University, New York, New York 10021.

Nature
|September 23, 1993
PubMed
まとめ

プロトオンコタンパク質Mycは,転写因子TFII-Iと相互作用し,特定のプロモーター要素での転写開始を阻害する. この相互作用は,必須の転写複合体の形成を防止し,細胞増殖と分化に影響を与えます.

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