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Updated: Aug 2, 2026

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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ガンマインターフェロンとMHC遺伝子の発現は,プロテアソームによるペプチド水解を調節する

M Gaczynska1, K L Rock, A L Goldberg

  • 1Harvard Medical School, Department of Cellular and Molecular Physiology, Boston, Massachusetts 02115.

Nature
|September 16, 1993
PubMed
まとめ

ガンマインターフェロン (IFN) は,プロテアソームの活動を変化させ,免疫システムのプレゼンテーションに不可欠なペプチドの生成を強化します. この改変は,MHCクラスI分子に必要な特定のペプチドの生成を好む.

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