関連する実験動画

Updated: May 12, 2026

Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy
12:03

Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy

Published on: September 5, 2016

HIV-1 Revタンパク質のRNA結合を選択的にブロックする小分子は,Rev機能を阻害し,ウイルス産生を阻害する

M L Zapp1, S Stern, M R Green

  • 1Program in Molecular Medicine, University of Massachusetts Medical Center, Worcester 01605.

Cell
|September 24, 1993
PubMed
まとめ

ネオミシンBのような特定のアミノグリコシド抗生物質は,ヒト免疫不全ウイルス (HIV) のRevタンパク質がウイルスRNAに結合することをブロックすることができます. この発見は,RNAとタンパク質の相互作用を標的とした選択的な抗ウイルス薬の開発のための新しい戦略を提供します.

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Identification of Nucleolar Factors During HIV-1 Replication Through Rev Immunoprecipitation and Mass Spectrometry09:38

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