グルコースは,禁食中のヒトに注入されたアミノ酸から全身のタンパク質合成を促進します. イソトープの実証を行いました
Lancet (London, England)
|January 1, 1979
まとめ
アミノ酸注入にグルコースを加えると,全身のタンパク質合成が増加します. 禁食中の男性. タンパク質の分解は安定したままであったが,窒素の周回量は,経口摂取と比較して静脈内投与で予想外に減少した.
科学分野:
- メタボリズムは
- 栄養科学 栄養学 栄養科学は,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学が,栄養学は,栄養学が,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は,栄養学は
- 生理学 生理学とは
背景:
- 栄養素の代謝を理解することは,臨床栄養において極めて重要です.
- タンパク質と窒素の循環に対する静脈注入の栄養の影響については,さらなる調査が必要である.
研究 の 目的:
- アミノ酸注入へのグルコース添加が,禁食中の男性におけるタンパク質の合成と分解に及ぼす影響を調査する.
- 経口栄養から親腸栄養への移行期間中の全身窒素回転の変化を調べる.
主な方法:
- 15N-グリシン恒定注入技術を使用しました.
- 測定された高原尿素濃縮は,エンドポイントとして.
- 経口摂取と2つの静脈注入栄養プログラムとの比較結果.
主要な成果:
- アミノ酸注入にグルコースを加えると,全身タンパク質合成が有意に増加した.
- 全身タンパク質の分解率は変わらない.
- 経口から静脈注入の餌への移行時に,これまで報告されていない全体窒素周回量の減少が観察されました.
結論:
- グルコースの投与は,断食中のアミノ酸注入の文脈でタンパク質合成を強化します.
- 腸内栄養中の窒素回転の減少は,胃腸酵素合成の減少と腸細胞回転の減少に関連している可能性があります.
関連する概念動画
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