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Updated: Aug 11, 2026

Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies
12:05

Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies

Published on: March 6, 2013

ディスルフイド結合形成に必要なDsbAタンパク質の結晶構造は,in vivoで

J L Martin1, J C Bardwell, J Kuriyan

  • 1Rockefeller University, New York, New York.

Nature
|September 30, 1993
PubMed
まとめ

細菌のタンパク質DsbAは,システイン残基を酸化することによって,タンパク質の折り畳みを加速します. その結晶構造は,独特のドメイン配列を明らかにし,硫化二酸化物結合形成の前に,展開されたタンパク質に結合することを示唆しています.

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