関連する実験動画

Updated: Jul 16, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
16:24

Analyzing and Building Nucleic Acid Structures with 3DNA

Published on: April 26, 2013

亜鉛指のモチーフを含む核毛孔複合タンパク質で,DNAを結合し,核プラズマと向き合う

J Sukegawa1, G Blobel

  • 1Howard Hughes Medical Institute, Rockefeller University, Laboratory of Cell Biology, New York, New York 10021.

Cell
|January 15, 1993
PubMed
まとめ

研究者らは,ユニークな亜鉛指ドメインを含む新しいネズミの肝臓タンパク質 nup153 を特定しました. このタンパク質はDNAを結合し,核孔複合体に位置し,ゲノム組織と遺伝子ゲートに役割を果たしていることを示唆しています.

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The Nucleus01:32

The Nucleus

The nucleus is a membrane-bound organelle that acts as a control center in a eukaryotic cell. It contains chromosomal DNA, which controls gene expression and precisely regulates the production of proteins within the cell. In contrast, the DNA inside the mitochondria and chloroplast only carries out functions that are specific to those organelles.
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The regulation of gene expression inside the nucleus is dependent on many factors, including the DNA structure. The...
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Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
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DNA Packaging00:58

DNA Packaging

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The Nucleus01:25

The Nucleus

The nucleus is a membrane-bound organelle that acts as a control center in a eukaryotic cell. It contains chromosomal DNA, which controls gene expression and precisely regulates the production of proteins within the cell. In contrast, the DNA inside the mitochondria and chloroplast only carries out functions that are specific to those organelles.
Arrangement of DNA within Nucleus
The regulation of gene expression inside the nucleus is dependent on many factors, including the DNA structure. The...
Nucleoid01:24

Nucleoid

The nucleoid represents a structurally and functionally distinct region within prokaryotic cells, where the cell's DNA and associated proteins are housed. Unlike eukaryotic cells, prokaryotes lack a membrane-bound nucleus, and the nucleoid facilitates the organization and accessibility of the genetic material within this constraint. The DNA in most bacteria and archaea exists as a single, circular, double-stranded molecule that is highly compacted through supercoiling and interactions with...