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Updated: Jun 12, 2026

Combined Genetic and Chemical Capsid Modifications of Adenovirus-Based Gene Transfer Vectors for Shielding and Targeting
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アデノウイルスプロテアゼは,ウイルスにコードされたディスルフィド結合ペプチドによって活性化されます

A Webster1, R T Hay, G Kemp

  • 1Division of Biochemistry and Molecular Biology, School of Biological and Medical Sciences, University of St. Andrews, Scotland.

Cell
|January 15, 1993
PubMed
まとめ

ウイルスの感染性にとって不可欠なアデノウイルスプロテアゼは,活性化のためにウイルスペプチド (pVI) を必要とします. この新しいメカニズムは,チオール-ジスルフィドの交換を伴うもので,ウイルスプロテアゼの活動を制御するための新しい戦略を強調しています.

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