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Updated: May 3, 2026

Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC Crosslinking of Small Molecules to Isolate Chromatin
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高親近性DNA結合のMycの類似体:アルファヘリックスによる認識

D E Fisher1, L A Parent, P A Sharp

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.

Cell
|February 12, 1993
PubMed
まとめ

研究者らは,DNA結合に不可欠な基本ヘリックス・ループ・ヘリックス・ルシンのジッパー (b-HLH-ZIP) タンパク質に含まれる重要なアミノ酸を特定した. 変異変異の研究は,CACGTG配列に対するDNA結合親和性を高める戦略を明らかにした.

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