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Updated: Jul 7, 2026

In Vitro Assay to Evaluate the Impact of Immunoregulatory Pathways on HIV-specific CD4 T Cell Effector Function
09:26

In Vitro Assay to Evaluate the Impact of Immunoregulatory Pathways on HIV-specific CD4 T Cell Effector Function

Published on: October 15, 2013

ヒト免疫不全ウイルスによる細胞分化誘発 1 vpr

D N Levy1, L S Fernandes, W V Williams

  • 1Department of Medicine, University of Pennsylvania, Philadelphia.

Cell
|February 26, 1993
PubMed
まとめ

HIV-1 vpr遺伝子は,ヒトのラブドミオサルコマ細胞の分化を引き起こし,細胞の拡大を引き起こし,増殖を停止させます. これは,VPRが細胞機能を妨害することによって,HIVの病原化に役割を果たす可能性があることを示唆しています.

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