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Updated: Jul 30, 2026

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model
09:42

A Fibrin-Enriched and tPA-Sensitive Photothrombotic Stroke Model

Published on: June 4, 2021

血栓を標的とするプラズミノゲン活性化剤の血栓解離性プロファイル. 効力を決定するパラメータ,および初期および最大速度

P Holvoet1, M Dewerchin, J M Stassen

  • 1Center for Thrombosis and Vascular Research, University of Leuven, Belgium.

Circulation
|March 1, 1993
PubMed
まとめ

リコンビナント単鎖ウロキナーゼ型プラズミノゲン活性化剤 (rscu-PA) を,フィブリン特異抗体で標的にすることで,その血栓解離作用が強化されます. このアプローチは,最大溶解率や遅延期を変化させることなく,凝固標的を改善し,血栓解離療法のための有望な戦略を提供します.

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