人間のU1 snRNP特異のU1Aタンパク質は,自身のプレ-mRNAのポリアデニレーションを阻害する

関連する実験動画

Updated: May 11, 2026

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

W C Boelens1, E J Jansen, W J van Venrooij

  • 1Department of Biochemistry, University of Nijmegen, The Netherlands.

Cell
|March 26, 1993
PubMed
まとめ

U1Aタンパク質は,その3'未翻訳領域 (UTR) と結合し,ポリアデニレーションを阻害することによって,自身のmRNA生成を調節する. この保存されたメカニズムは種間で観察され,新しい自己調節経路を強調しています.

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