関連する実験動画

Updated: Jun 19, 2026

Using the E1A Minigene Tool to Study mRNA Splicing Changes
10:25

Using the E1A Minigene Tool to Study mRNA Splicing Changes

Published on: April 22, 2021

接合部位の選択と接合効率は,酵母におけるプレ-mRNAの分子内塩基配列によって,好ましい影響を受けます

V Goguel1, M Rosbash

  • 1Howard Hughes Medical Institute, Department of Biology, Brandeis University, Waltham, Massachusetts 02254.

Cell
|March 26, 1993
PubMed
まとめ

mRNA前スプライシングメカニズムを調査したこの研究では,スプライシングサイト選択に影響を与える文脈効果が明らかになりました. 塩基ペアリングを含む長距離相互作用は,酵母におけるスプライシング効率とパートナー割り当てに大きな影響を与えます.

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Splicing is the process by which eukaryotic RNA is edited before its translation into protein. The RNA strand transcribed from eukaryotic DNA is called the primary transcript. The primary transcripts that become mRNAs are called precursor messenger RNAs (pre-mRNAs). Eukaryotic pre-mRNA contains alternating sequences of exons and introns. Exons are nucleotide sequences that code for proteins, whereas introns are the non-coding regions. In RNA splicing, introns are removed and exons are bonded...
RNA Splicing01:32

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Alternative RNA Splicing

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Pre-mRNA Processing: RNA Splicing

Splicing is the process by which eukaryotic RNA is edited before its translation into protein. The RNA strand transcribed from eukaryotic DNA is called the primary transcript. The primary transcripts that become mRNAs are called precursor messenger RNAs (pre-mRNAs). Eukaryotic pre-mRNA contains alternating sequences of exons and introns. Exons are nucleotide sequences that code for proteins, whereas introns are the non-coding regions. In RNA splicing, introns are removed and exons are bonded...
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