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人間のSos1は,GRB2に結合するRasのためのグアニンヌクレオチド交換因子であり,GRB2に結合する

P Chardin1, J H Camonis, N W Gale

  • 1Institut de Pharmacologie Moleculaire et Cellulaire, CNRS, Valbonne, France.

Science (New York, N.Y.)
|May 28, 1993
PubMed
まとめ

研究者らは,Ras信号伝達に不可欠なヒトのタンパク質であるhSos1を特定した. グアニンヌクレオチド交換因子として作用し,GRB2と相互作用し,受容体チロシンキナーゼをRas経路に結合させます.

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