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Updated: Jun 30, 2026

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors
10:59

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

Published on: February 11, 2014

内向整流器のカリウムチャネルにGタンパク質調節を与えるドメインの識別

M T Kunkel1, E G Peralta

  • 1Department of Molecular and Cellular Biology Harvard University Cambridge, Massachusetts 02138, USA.

Cell
|November 3, 1995
PubMed
まとめ

グアニンヌクレオチド結合 (G) タンパク質ベータ・ガンマサブユニットは,心臓の内向整流器のカリウムチャンネル (IRK) を調節する. 研究者らは,チャンネル孔の近くの配列,特にカルボキシル末端の内部の配列が,このGベータ・ガンマサブユニット相互作用とチャンネル調節に決定的であることを確認した.

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