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Updated: May 7, 2026

Mouse Genome Engineering Using Designer Nucleases
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プロスタグランジン合成酵素2遺伝子の障害は,マウスで重度の腎臓病理を引き起こす

S G Morham1, R Langenbach, C D Loftin

  • 1Department of Pathology, University of North Carolina at Chapel Hill 27599-7525, USA.

Cell
|November 3, 1995
PubMed
まとめ

サイクロオキシゲナーゼ2 (COX-2) が欠けているマウスは,正常な炎症反応を示しますが,腎臓疾患と炎を発症します. これは,COX-2が炎症以外の役割を持っていることを示唆しています.

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