コミュニティで得られた肺炎の患者の予後とアウトカム メタアナリシスです
M J Fine1, M A Smith, C A Carson
1Department of Medicine, University of Pittsburgh, Pa., USA.
JAMA
|January 10, 1996
まとめ
地域感染性肺炎 (CAP) は,特に集中治療室では高い死亡率を有しています. 男性の性別,低体温,神経疾患などの予後要因は,CAP患者の死亡リスクを大幅に増加させます.
科学分野:
- 肺内科 肺内科 肺内科
- クリティカルケア・メディシン
- エピデミオロジー エピデミオロジー
背景:
- コミュニティで得られた肺炎 (CAP) は,世界中で罹病率と死亡率の重要な原因です.
- CAPの予後と結果を理解することは,効果的な患者管理に不可欠です.
研究 の 目的:
- コミュニティで得られた肺炎 (CAP) と診断された患者の予後とアウトカムに関する既存の医学文献を体系的にレビューする.
主な方法:
- 広範なMEDLINE検索により,CAPの予測に関する英語の研究が特定されました.
- 大人のCAP患者を含む127の研究コホートに関する報告する122件の論文を分析した.
- 死亡率に関連する予後要因の質的評価とメタ分析は,オッズ比率 (ORs) とレート差 (RDs) を用いて行われました.
主要な成果:
- 127コホートにおけるCAP患者の全死亡率は13.7%で,ICU患者の死亡率は36.5%であった.
- 低体温,低血圧,腫瘍性疾患,神経疾患を含む11の予後要因は,死亡率の増加と有意に関連していました.
- 死亡率は肺炎の病因によって大きく変化し,2%未満から30%以上であった.
結論:
- CAPの入院患者は,コホート特性,病因学,および特定の予後要因の影響を受ける高死亡率に直面します.
- 外来CAP患者における非死亡率に関するデータは限られているため,研究結果を一般化する際には注意が必要である.
関連する概念動画
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