新しいβ1-インテグリン結合タンパク質キナーゼによる細胞粘着とアンカレーズ依存の成長の調節

G E Hannigan1, C Leung-Hagesteijn, L Fitz-Gibbon

  • 1Cancer Biology Research Program, Sunnybrook Health Science Centre, University of Toronto, Ontario, Canada.

Nature
|January 4, 1996
PubMed
まとめ

研究者は,ベータ1-インテグリンと相互作用することにより,細胞粘着と成長を調節する上で重要な役割を果たす新しいセリン/スレオニンキナーゼであるインテグリン結合キナーゼ (ILK) を特定しました. この発見は,インテグリン媒介信号伝導経路に光を当てています.

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