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Updated: Aug 17, 2026

The Assembly and Application of 'Shear Rings': A Novel Endothelial Model for Orbital, Unidirectional and Periodic Fluid Flow and Shear Stress
09:20

The Assembly and Application of 'Shear Rings': A Novel Endothelial Model for Orbital, Unidirectional and Periodic Fluid Flow and Shear Stress

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Egr-1-誘発の内皮基因発現:血管損傷における一般的なテーマ

L M Khachigian1, V Lindner, A J Williams

  • 1Vascular Research Division, Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.

Science (New York, N.Y.)
|March 8, 1996
PubMed
まとめ

早期成長応答遺伝子1 (Egr-1) は,動脈損傷後の血小板由来成長因子B鎖 (PDGF-B) および他の遺伝子の上位調節に不可欠です. Egr-1はSp1を位移させ,損傷した内皮細胞におけるこれらの強力な媒介者の発現を媒介する.

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