関連する実験動画

Updated: Jul 25, 2026

A High-throughput Cre-Lox Activated Viral Membrane Fusion Assay to Identify Inhibitors of HIV-1 Viral Membrane Fusion
07:22

A High-throughput Cre-Lox Activated Viral Membrane Fusion Assay to Identify Inhibitors of HIV-1 Viral Membrane Fusion

Published on: August 14, 2018

リンパ球におけるHIV-1複製の抑制は,RevコファクターeIF-5Aの変異によって引き起こされる

D Bevec1, H Jaksche, M Oft

  • 1Sandoz Research Institute, Department of Immunodermatology, Vienna, Austria.

Science (New York, N.Y.)
|March 29, 1996
PubMed
まとめ

非機能性ユーカリオット開始因子5A (eIF-5A) ミュータントは,HIV-1の複製を阻害しました. これらのeIF-5A変異体はRevトランス活性化と核輸出を阻害し,HIV-1に対する潜在的な治療標的を提供した.

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