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Updated: Jun 23, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
13:58

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells

Published on: October 22, 2012

一つのMHC/ペプチドリガンドによって形作られるT細胞のレパートリー

L Ignatowicz1, J Kappler, P Marrack

  • 1Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine, University of Colorado Health Sciences Center, Denver, 80206, USA.

Cell
|February 23, 1996
PubMed
まとめ

数少ない未成熟のチモサイトが,胸腺で成熟する. 発達を制限すると考えられるポジティブ・セレクションは,実際には多くの細胞が成熟することを可能にしますが,これらの細胞は後に自己ペプチドとの交叉反応により死亡し,T細胞のレパートリーを制限します.

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