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Updated: Jul 6, 2026

Cell Type-specific Gene Expression Profiling in the Mouse Liver
10:06

Cell Type-specific Gene Expression Profiling in the Mouse Liver

Published on: September 17, 2019

肝細胞核因子1の不活性化により,肝機能不全,フェニルケトヌーリア,腎臓ファンコーニ症候群が発生する

M Pontoglio1, J Barra, M Hadchouel

  • 1Unité des Virus Oncogènes, Département des Biotechnologies, InstitutPasteur, Paris, France.

Cell
|February 23, 1996
PubMed
まとめ

肝細胞核因子1 (HNF1) が欠けているマウスは,肝臓の拡大と衰えを示し,フェニルケトンウリアとファンコニ症候群を引き起こす. これらのHNF1欠乏したマウスは,ヒト腎臓ファンコーニ症候群の研究に貴重なモデルとして役立つ.

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