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ロタウイルス性非構造性グリコタンパク質によって誘発された年齢依存性下痢

J M Ball1, P Tian, C Q Zeng

  • 1Division of Molecular Virology, Baylor College of Medicine, Houston, TX 77030, USA.

Science (New York, N.Y.)
|April 5, 1996
PubMed
まとめ

ロタウイルスの非構造性グリコタンパク質NSP4は,ウイルス性腸毒素として作用し,腸内のカルシウム依存の塩化物分泌を誘発することによって下痢を引き起こす. マウスにおけるこの疾患への反応は,年齢と投与量に依存することが判明しました.

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