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Updated: May 6, 2026

An In Vitro Dormancy Model of Estrogen-sensitive Breast Cancer in the Bone Marrow: A Tool for Molecular Mechanism Studies and Hypothesis Generation
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線維細胞成長因子受容体3は,骨の成長の負の調節体である

C Deng1, A Wynshaw-Boris, F Zhou

  • 1Department of Genetics, Harvard Medical School, Boston, Massachusetts, 02115, USA.

Cell
|March 22, 1996
PubMed
まとめ

線維細胞成長因子受容体3 (FGFR-3) は,骨発達の重要なプロセスである内軟骨骨化を否定的に調節する. マウスのFgfr-3遺伝子を破壊すると,骨の成長が促進され,FGFR-3が骨の形成を制限することを示唆しています.

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