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Updated: Aug 9, 2026

Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells
10:34

Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells

Published on: April 14, 2010

IL-4誘発のTh2応答の欠如と,Stat6遺伝子が破壊されたマウスのIgEクラス交換

K Shimoda1, J van Deursen, M Y Sangster

  • 1Department of Biochemistry, St Jude Children's Research Hospital, Memphis, Tennessee 38105 USA.

Nature
|April 18, 1996
PubMed
まとめ

シグナルトランスデューサーとトランスクリプション6 (Stat6) のアクティベーターは,インタールイキン-4 (IL-4) 機能を媒介する. Stat6nullマウスは,Th2の分化とIgEのスイッチングの欠陥を示し,Stat6nullマウスを確認した.

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