関連する実験動画

Updated: Jul 15, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
13:55

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization

Published on: February 3, 2013

RAG1およびRAG2タンパク質は,V(D) J再結合において12/23ルールを確立する

D C van Gent1, D A Ramsden, M Gellert

  • 1Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Cell
|April 5, 1996
PubMed
まとめ

RAGタンパク質は,V(D) J再結合特異性を制御する. Mg2+のような金属イオンは,割れ方のために12/23のシグナル配列の両方を必要とし,Mn2+は1つだけで割れることを可能にします.

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Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae07:55

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