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Updated: May 8, 2026

Pull-down of Calmodulin-binding Proteins
07:51

Pull-down of Calmodulin-binding Proteins

Published on: January 23, 2012

カルモジュリンとNR1サブユニットとの直接的な相互作用により,NMDA受容体の不活性化

M D Ehlers1, S Zhang, J P Bernhadt

  • 1Department of Neuroscience, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Cell
|March 8, 1996
PubMed
まとめ

カルモジュリンは,N-メチル-D-アスパルテート (NMDA) 受容体と直接結合し,カルシウムに依存し,そのチャネル活動を低下させます. この相互作用は,脳内のNMDA受容体の機能を調節する新しいメカニズムを示唆しています.

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