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Updated: Aug 7, 2026

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination
12:33

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination

Published on: June 25, 2014

アデノシン・ディフォスファートは,インスリン分泌の細胞内調節剤として作用する

C G Nichols1, S L Shyng, A Nestorowicz

  • 1Department of Cell Biology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. cnichols@cellbio.wustl.edu

Science (New York, N.Y.)
|June 21, 1996
PubMed
まとめ

サルフォニル尿素受容体NBF2の変異は,アデノシン三酸塩感受性カリウム (KATP) 経路が代謝変化に反応し,インスリン分泌に影響を与える方法を乱します. 細胞内MgADPは,SUR NBF2.2に結合することで,これらのチャネルを調節する可能性があります.

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