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Updated: Aug 14, 2026

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
15:33

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation

Published on: August 13, 2013

T細胞受容体数と調節可能な値によって決定されるT細胞活性化

A Viola1, A Lanzavecchia

  • 1Basel Institute for Immunology, Switzerland.

Science (New York, N.Y.)
|July 5, 1996
PubMed
まとめ

T細胞は,リガンドに関係なく,約8000のトリガーされたT細胞受容体 (TCR) を数えるときに活性化します. コスティミュレータ信号は,この値を大幅に低下させ,T細胞の抗原に対する感受性を高めます.

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