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Updated: Aug 6, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
08:49

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

Published on: January 22, 2019

リンパ球アポトーシス:イノシトール1,4,5-トリフォスファート型3受容体の増加によって媒介される

A A Khan1, M J Soloski, A H Sharp

  • 1Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Science (New York, N.Y.)
|July 26, 1996
PubMed
まとめ

イノシトール1,4,5-トリスホスファート受容体 (IP3R),特にタイプ3 (IP3R3) は,リンパ球アポトーシス中に増加する. このIP3R3のアップレギュレーションは,それをブロックするとアポトーシスを防ぐので,プログラムされた細胞死にとって非常に重要です.

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