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Updated: Jul 10, 2026

Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients
08:10

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Published on: December 14, 2015

HoxD複合体の遺伝子転置は,規制制御の階層を明らかにする

F van der Hoeven1, J Zákány, D Duboule

  • 1Department of Zoology and Animal Biology, University of Geneva, Switzerland.

Cell
|June 28, 1996
PubMed
まとめ

脊椎動物のホックス遺伝子は,そのクラスター順序に関連した一時的活性化を示す. Hoxd遺伝子の移転は,共有された規制要素と新しい干渉を明らかにし,高次元の規制がHox遺伝子のクラスタリングを維持することを示唆しました.

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Regulation of Expression Occurs at Multiple Steps02:24

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Gene expression can be regulated at almost every step from gene to protein. Transcription is the step that is most commonly regulated. This involves the binding of proteins to short regulatory sequences on the DNA. This association can either promote or inhibit the transcription of a gene associated with the respective sequence.
Transcription results in the generation of precursor (pre-mRNA) that consists of both exons and introns, which needs further processing before being translated to a...
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