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Updated: Aug 2, 2026

Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes
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ディメリゼーションによる受容体タンパク質-チロシン・フォスファタゼ-アルファの抑制のための構造的基礎

A M Bilwes1, J den Hertog, T Hunter

  • 1Structural Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.

Nature
|August 8, 1996
PubMed
まとめ

受容体型のタンパク質・チロシン・フォスファタゼ (RPTPs) の活動は,二分化によって調節される. 構造分析によると,N端セグメントは活性部位をブロックし,RPTP機能をダウンレギュレーションする可能性がある.

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