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Updated: Jul 10, 2026

An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy
07:45

An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy

Published on: October 21, 2014

ギャラクトセレブロシドとスルファチドがない場合のミエリン化:異常な機能と地域的不安定性を持つ正常な構造

T Coetzee1, N Fujita, J Dupree

  • 1UNC Neuroscience Center, University of North Carolina at Chapel Hill 27599, USA.

Cell
|July 26, 1996
PubMed
まとめ

ギャラクトセレブロシド (GalC) と硫化物合成が欠けているマウスは,まだミエリンを形成しますが,不安定です. この研究は,これらの脂質がミエリン整合性と神経系の機能を維持する上で果たす重要な役割を明らかにしています.

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