関連する実験動画

Updated: Jul 27, 2026

Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography
10:50

Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography

Published on: March 9, 2010

グルコース由来タンパク質のクロスリンクを in vitro および in vivo で分裂する剤

S Vasan1, X Zhang, X Zhang

  • 1The Picower Institute for Medical Research, Manhasset, New York 11030, USA.

Nature
|July 18, 1996
PubMed
まとめ

進糖化最終産物 (AGEs) は,糖とタンパク質の反応から形成され,クロスリンクを引き起こし,老化と糖尿病の合併症に寄与します. N-フェナシルチアゾリウムブロミド (PTB) は,これらのAGEクロスリンクを効果的に破壊し,潜在的な治療戦略を提供します.

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Genetic and Biochemical Approaches for In Vivo and In Vitro Assessment of Protein Oligomerization: The Ryanodine Receptor Case Study

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