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Updated: Aug 16, 2026

Peptide-based Identification of Functional Motifs and their Binding Partners
14:28

Peptide-based Identification of Functional Motifs and their Binding Partners

Published on: July 1, 2013

リンパ球化学吸引剤SDF-1は,LESTR/fusinのリガンドであり,HIV-1の侵入を阻害する

C C Bleul1, M Farzan, H Choe

  • 1The Center for Blood Research, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

Nature
|August 29, 1996
PubMed
まとめ

ストロマル細胞由来因子-1 (SDF-1),CXCキモカインはCXCキモカイン受容体-4 (CXCR-4) と結合し,T型HIV-1感染を抑制する. この発見は,リンパ球の移動とウイルスの侵入経路におけるSDF-1の役割を強調しています.

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SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry

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