関連する実験動画

Updated: May 12, 2026

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
07:27

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

Published on: April 30, 2010

E. coli RNAポリメラーゼシグマファクターシグマ70の機能は,プロモーター-近接パウシングにおける

B Z Ring1, W S Yarnell, J W Roberts

  • 1Section of Biochemistry, Molecular and Cell Biology Cornell University Ithaca, New York 14853, USA.

Cell
|August 9, 1996
PubMed
まとめ

E. coli RNAポリメラーゼのシグマ70因子は,延長中の転写パウスを誘発する. この一時停止は,特定のDNA配列によって媒介され,シグマ70がテンプレートでないDNA鎖に結合することを要求します.

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関連する概念動画

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Bacterial Transcription01:53

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Bacterial RNA Polymerase00:43

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Unlike eukaryotes, bacteria use a single RNA Polymerase (RNAP) to transcribe all genes. The different subunits of bacterial RNAPhave distinct functions. The multisubunit structure of the bacterial RNAP helps the enzyme to maintain catalytic function, facilitate assembly, interact with DNA and RNA, and self-regulate its activity.
In most genes, the transcription site is a single base present upstream of the coding sequence. Though RNAP is a catalytically efficient enzyme, it does not recognize...
Transcription Elongation Factors02:35

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Transcription elongation is a dynamic process that alters depending upon the sequence heterogeneity of the DNA being transcribed. Hence, it is not surprising that the elongation complex's composition also varies along the way while transcribing a gene.
The transcription elongation is regulated via pausing of RNA polymerase on several occasions during transcription. In bacteria, these halts are necessary because the transcription of DNA into mRNA is coupled to the translation of that mRNA into a...
Transcription in Prokaryotes01:28

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