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Updated: Jul 13, 2026

Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based Reporters
09:22

Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based Reporters

Published on: November 26, 2013

TBP関連因子は,一般的に酵母における転写活性化には必要ありません

Z Moqtaderi1, Y Bai, D Poon

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|September 12, 1996
PubMed
まとめ

TFIID TBP関連因子 (TAFs) は酵母成長には不可欠ですが,転写の活性化には一般的に必要とされません. TAFの枯渇は,いくつかのTATA-lessプロモーターに影響を与え,遺伝子調節における特定の役割を明らかにします.

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Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
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Prokaryotic Transcriptional Activators and Repressors

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