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Updated: Aug 8, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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インターフェロン-アルファによって誘発されたシグナル伝達におけるStat2とp300/CBPの協力

S Bhattacharya1, R Eckner, S Grossman

  • 1Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|September 26, 1996
PubMed
まとめ

アデノウイルスE1Aタンパク質は,Stat2とp300/CBPの相互作用を阻害することによって,インターフェロン-アルファ (IFN-アルファ) ウイルス対策反応を抑制する. この障害は,細胞防衛遺伝子の活性化を阻害し,ウイルスの複製を助けます.

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