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Updated: Aug 8, 2026

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing
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Published on: January 22, 2019

Tat-SF1:HIV-1 Tatによる転写延長の刺激のためのコファクター

Q Zhou1, P A Sharp

  • 1Center for Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Science (New York, N.Y.)
|October 25, 1996
PubMed
まとめ

研究者らは,ヒト免疫不全ウイルス1型 (HIV-1) Tatのトランス活性化に不可欠な細胞因子であるTat-SF1を特定した. キナーゼの基質であるTat-SF1は,タットと相互作用してウイルスの遺伝子発現を高めます.

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