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Updated: Oct 13, 2026

Protein Misfolding Cyclic Amplification of Prions
10:12

Protein Misfolding Cyclic Amplification of Prions

Published on: November 7, 2012

プリオン菌株の変異の分子分析と"新変異"CJDの病因学

J Collinge1, K C Sidle, J Meads

  • 1Neurogenetics Unit, Department of Biochemistry and Molecular Genetics, Imperial College School of Medicine at St. Mary's, London, UK. j.collinge@ic.ac.uk

Nature
|October 24, 1996
PubMed
まとめ

新型変異型クレッツフェルト・ヤコブ病 (vCJD) のように,伝染性スポンジ状脳症の異なる株は,異なるプリオンタンパク質 (PrPSc) 特性を示しています. これらの特徴は,プリオンタンパク質自体が病気をコードし,BSEがvCJDと関連していることを示唆しています.

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