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Updated: Aug 12, 2026

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea
07:07

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea

Published on: February 21, 2016

HoxD複合体の標的型欠乏症のマウスにおけるシンポリダクティリア

J Zákány1, D Duboule

  • 1Department of Zoology and Animal Biology, University of Geneva, Sciences III, Switzerland.

Nature
|November 7, 1996
PubMed
まとめ

マウスのHoxd-11,Hoxd-12,Hoxd-13遺伝子を同時に無効化すると,指の発達が妨げられ,骨格の欠陥が生じます. この研究は,ヒトのシンポリダクティリアとHoxd遺伝子の機能的階層に関する洞察を提供します.

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