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Updated: May 7, 2026

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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Bcl-2は,タンパク質キナーゼRaf-1をミトコンドリアに標的にする

H G Wang1, U R Rapp, J C Reed

  • 1The Burnham Institute, Program on Apoptosis and Cell Death Research, La Jolla, California 92037, USA.

Cell
|November 15, 1996
PubMed
まとめ

Bcl-2タンパク質は,Raf-1キナーゼをミトコンドリアに標的とし,BADをリン酸化することによって細胞死を防ぐ. このミトコンドリアの局所化は,Bcl-2にとって極めて重要です.

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