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Updated: Jul 28, 2026

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膜タンパク質が,エンドプラズマ網膜から,破壊のためにプロテアソームにSec61媒介で移転される

E J Wiertz1, D Tortorella, M Bogyo

  • 1Center for Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA.

Nature
|December 5, 1996
PubMed
まとめ

ヒューマン・サイトメガロウイルス (HCMV) は,US2タンパク質を使用して,メジャー・ヒストコンパティビリティ・コンプレックス (MHC) クラスIの分子を分解します. このプロセスは,Sec61複合体経由で,エンドプラズマ網膜からサイトゾールへの脱位を伴う.

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