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Updated: Aug 11, 2026

Real-time Live Imaging of T-cell Signaling Complex Formation
10:31

Real-time Live Imaging of T-cell Signaling Complex Formation

Published on: June 23, 2013

ヒトリンパ球キナーゼの活性化のための構造的基礎 Lck はチロシンリン酸化過程で発生する

H Yamaguchi1, W A Hendrickson

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York 10032, USA.

Nature
|December 5, 1996
PubMed
まとめ

活性化されたLckチロシンキナーゼの結晶構造は,Tyr 394のリン酸化によって,機能的な活性部位がどのように作られるかを明らかにしています. この発見は,T細胞の免疫応答の調節と潜在的な阻害メカニズムに関する洞察を提供します.

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